1.Glycolysis
|
| Gene Name |
Locus |
| Glucokinase (Hexokinase 4) |
7p13 |
| Glucose 6-phosphatase |
17q21.31 |
| Hexokinase 1 |
10q22.1 |
| Hexokinase 2 |
2p12 |
| Hexokinase 3 |
5q35.2 |
| Phosphoglucose isomerase |
19q13.11 |
| Phosphofructokinase, Liver Type |
21q22.3 |
| Fuctose-1,6-bisphosphatase |
9q22.32 |
| Aldolase A |
16p11.2 |
| Aldolase B |
9q31.1 |
| Aldolase C |
17q11.2 |
| Triose phosphate isomerase |
12p13.31 |
| Glyceraldehyde 3-phosphate dehydrogenase |
12p13.31 |
| Phosphoglycerate kinase 1 |
Xq21.1 |
| Phosphoglycerate mutase |
10q24.1 |
| Enolase 1 |
1p36.23 |
| Enolase 2 |
12p13.31 |
| Enolase 3 |
17p13.2 |
| Pyruvate kinase, liver and RBC |
1q22 |
2.TCA cycle
|
| Gene Name |
Locus |
| Aconitase |
22q13.2 |
| Isocitrate dehydrogenase |
15q26.1 |
| alpha-ketoglutarate dehydrogenase |
7p13 |
| dihydrolipoyl dehydrogenase |
7q31.1 |
| dihydrolipoyl succinyltransferase |
14q24.3 |
| succinate-CoA Ligase, alpha subunit |
2p11.2 |
| Succinate-CoA Ligase, ADP-Forming, beta subunit |
13q14.2 |
| Succinate dehydrogenase |
5p15.33 |
| Fumarase |
1q43 |
| Malate dehydrogenase |
7q11.23 |
| Citrate synthase |
12q13.3 |
3.Pentose phosphate pathway
|
| Gene Name |
Locus |
| Glucose-6-phosphate dehydrogenase |
Xq28 |
| 6-phosphogluconolactonase |
19p13.11 |
| 3-epimerase |
2q34 |
| ribose-5-phosphate isomerase |
2p11.2 |
| transketolase |
3p21.1 |
| transaldolase |
11p15.5 |
| Phosphohexose isomerase |
19q13.11 |
| aldolase A |
16p11.2 |
| aldolase B |
9q31.1 |
| aldolase C |
17q11.2 |
| triose-phosphate isomerase |
12p13.31 |
| fructose 1,6-bisphosphatase |
9q22.32 |
| phosphohexose isomerase |
19q13.11 |
4.Urea cycle
|
| Gene Name |
Locus |
| Carbamoyl phoshpate synthase I |
2q34 |
| Ornithine transcarbamylase |
Xp11.4 |
| Argininosuccinate synthase |
9q34.11 |
| Argininosuccinate lyase |
7q11.21 |
| Arginase |
6q23.2 |
5.Fatty acid metabolism
|
| Gene Name |
Locus |
| long-chain acyl-CoA synthetase |
4q35.1 |
| acyl-CoA dehydrogenase |
1p31.1 |
| acyl-CoA oxidase |
17q25.1 |
| enoyl-CoA hydratase |
10q26.3 |
| 3-hydroxyacyl-CoA dehydrogenase |
4q25 |
| long-chain 3-hydroxyacyl-CoA dehydrogenase |
2p23.3 |
| acetyl-CoA acyltransferase |
18q21.1 |
6.Purine biosynthesis
|
| Gene Name |
Locus |
| phosphoribosyl pyrophosphate synthetase |
Xq22.3 |
| phosphoribosy lpyrophosphate glutamyl amidotransferase |
4q12 |
| phosphoribosylglycinamide formyltransferase |
21q22.1 |
| phosphoribosylformylglycinamidine synthetase |
17p13.1 |
| phosphoribosylaminoimidazole carboxylase |
4q12 |
| phosphoribosylaminoimidazole synthase |
21q22.11 |
| adenylosuccinate lyase |
22q13.1 |
| 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase |
2q35 |
| IMP cyclohydrolase |
2q35 |
| adenylosuccinate synthetase |
1q44 |
| IMP dehydrogenase |
7q32.1 |
| GMP synthetase |
3q25.31 |
7.Pyrimidine biosynthesis
|
| Gene Name |
Locus |
| carbamoyl-phosphate synthase |
2p23.3 |
| aspartate transcarbamoylase |
2p23.3 |
| dihydroorotase |
2p23.3 |
| dihydroorotate dehydrogenase |
16q22.2 |
| orotate phosphoribosyltransferase |
3q21.2 |
| orotidylic decarboxylase |
3q21.1 |
| CTP synthase |
1p34.2 |
| ribonucletotide reductase, M1 subunit |
11p15.4 |
| ribonucletotide reductase, M2 subunit |
2p25.1 |
| thymidylate synthetase |
18p11.32 |
8.beta-oxdation of fatty acids
|
| Gene Name |
Locus |
| Acyl-CoA synthetase |
4q35.1 |
| Acyl-CoA dehydrogenase |
1p31.1 |
| delta2-enonl-CoA hydratase |
19q13.2 |
| L(+)-3-hydroxyacyl-CoA dehydrogenase |
4q25 |
| thiolase |
2p23.3 |
9.Biosynthethis of long chain fatty acids
|
| Gene Name |
Locus |
| Malonyl-CoA Decarboxylase |
16q23.3 |
| Acetyl CoA carboxylase |
17q12 |
| 3 ketoacyl synthase |
3p24.2 |
| 3 ketoacyl reductase |
Xp11.22 |
| Hydratase |
10q26.3 |
| Enoyl reductase |
19p13.12 |
| Thioesterase |
1p36.31 |
